Scientists have identified the Camp Hill virus, a henipavirus, in shrews in Alabama, marking its first detection in North America.
Researchers at the University of Queensland have discovered the first henipavirus detected in North America.
Dr. Rhys Parry from the School of Chemistry and Molecular Biosciences confirmed the presence of Camp Hill virus in shrews in Alabama, USA.
“Henipaviruses have caused serious disease and death in people and animals in other regions,” Dr Parry said
“One of the most dangerous is the Hendra virus, which was first detected in Brisbane, Australia, and has a fatality rate of 70 percent.
“Another example is Nipah virus which has recorded fatality rates between 40 and 75 per cent in outbreaks in Southeast Asia, including in Malaysia and Bangladesh.
“The discovery of a henipavirus in North America is highly significant, as it suggests these viruses may be more globally distributed than previously thought.”
Discovery in Northern Short-Tailed Shrews
Camp Hill virus was found in northern short-tailed shrews, a small mammal with wide distribution across Canada and the US.
Dr Parry said more research was needed to understand if it was a threat to people.
“The closest known henipavirus to Camp Hill virus that has caused disease in humans is Langya virus, which crossed from shrews to humans in China,” Dr Parry said.
“This indicates that shrew-to-human transmission can occur.”
Co-author Dr Ariel Isaacs said developing vaccines for the virus family was a focus for UQ researchers.
“The next step for this work is to characterize key surface proteins on the virus that are involved in cell entry to broaden our understanding of the virus family and identify better ways to protect against it,” Dr Isaacs said.
Reference: “Henipavirus in Northern Short-Tailed Shrew, Alabama, USA” by Rhys H. Parry, KayLene Y.H. Yamada, Wendy R. Hood, Yang Zhao, Jinlong Y. Lu, Andrei Seluanov, Vera Gorbunova, Naphak Modhiran, Daniel Watterson and Ariel Isaacs, February 2025, Emerging Infectious Diseases.
DOI: 10.3201/eid3102.241155
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